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Data Safety Monitoring Board recommended to discontinue trials due to unfavorable risk-benefit ratio
September 13, 2019
By: Kristin Brooks
Managing Editor, Contract Pharma
Eisai Co. and Biogen have decided to discontinue the Phase III clinical studies (MISSION AD1, AD2) on the investigational oral BACE inhibitor elenbecestat in patients with early Alzheimer’s disease (AD). The decision is based on the results of a safety review conducted by the Data Safety Monitoring Board (DSMB), which recommended to discontinue these trials due to unfavorable risk-benefit ratio. Dr. Lynn Kramer, Chief Clinical Officer, Neurology Business Group, Eisai Co., said: “...
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